Top cofit genes for PP_4977 from Pseudomonas putida KT2440

5,10-methylenetetrahydrofolate reductase
SEED: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
KEGG: methylenetetrahydrofolate reductase (NADPH)

Rank	Hit	Name	Description	Conserved?	Cofitness
1	PP_2375		cobalamin-dependent methionine synthase	0.99	0.89
2	PP_1681		cobalamin 5'-phosphate synthase / Cobalamin synthase	0.94	0.72
3	PP_3507		Aerobic cobaltochelatase subunit CobN	0.96	0.71
4	PP_4827		Precorrin-2 C(20)-methyltransferase	0.95	0.69
5	PP_1675		Subunit of adenosylcobinamide-phosphate synthase beta component	0.96	0.69
6	PP_1672		cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase	0.95	0.66
7	PP_4830		precorrin-6Y C(5,15)-methyltransferase	0.95	0.65
8	PP_1673		cobyrinate a,c-diamide synthase	0.96	0.64
9	PP_1677		Adenosyl-cobyric acid synthase	0.95	0.62
10	PP_4826		Precorrin-3B C17-methyltransferase	0.97	0.62
11	PP_1676		subunit of adenosylcobinamide-phosphate synthase beta component	0.93	0.60
12	PP_5203		5-formyltetrahydrofolate cyclo-ligase	0.96	0.57
13	PP_4832		Precorrin-6x reductase	0.96	0.56
14	PP_4829		putative precorrin-3B synthase	0.96	0.54
15	PP_1679		Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	0.96	0.54
16	PP_2001		O-succinylhomoserine sulfhydrylase	0.98	0.53
17	PP_5098		methionine biosynthesis protein MetW	0.98	0.53
18	PP_1025		2-isopropylmalate synthase	0.99	0.53
19	PP_5097		homoserine O-acetyltransferase	0.99	0.53
20	PP_1678		bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase	0.88	0.53

Or look for negative cofitness