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  • Top cofit genes for PP_4621 from Pseudomonas putida KT2440

    Homogentisate 1,2-dioxygenase
    SEED: Homogentisate 1,2-dioxygenase (EC 1.13.11.5)
    KEGG: homogentisate 1,2-dioxygenase

    Rank Hit Name Description Conserved? Cofitness  
    1 PP_3433 4-hydroxyphenylpyruvate dioxygenase 0.92 0.66
    2 PP_4619 Maleylacetoacetate isomerase 0.77 0.52
    3 PP_4489 sigma-54 dependent transcriptional regulator 0.89 0.49
    4 PP_3080 tyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase 0.35 0.48
    5 PP_3434 conserved protein of unknown function no 0.46
    6 PP_4620 Fumarylacetoacetase 0.66 0.44
    7 PP_3527 Transcriptional regulator, TetR family 0.29 0.37
    8 PP_4495 aromatic amino acid transport protein 0.88 0.36
    9 PP_3590 aromatic-amino-acid transaminase (EC 2.6.1.57) (from data) 0.48 0.34
    10 PP_3123 acetoacetyl CoA-transferase (subunit B) 0.56 0.26
    11 PP_1445 carbohydrate-selective porin 0.43 0.22
    12 PP_3121 transcriptional regulator, LysR family no 0.22
    13 PP_3122 acetoacetyl CoA-transferase (subunit A) 0.84 0.22
    14 PP_3555 putative Transmembrane sensor no 0.22
    15 PP_4011 isocitrate dehydrogenase, NADP(+)-specific 0.36 0.22
    16 PP_4333 CheW domain protein no 0.21
    17 PP_5236 conserved protein of unknown function no 0.20
    18 PP_1381 4-carboxymuconolactone decarboxylase 0.19 0.20
    19 PP_0850 Dual-specificity RNA methyltransferase RlmN 0.85 0.20
    20 PP_2098 D-alanyl-D-alanine carboxypeptidase no 0.20

    Or look for negative cofitness