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  • Top cofit genes for PP_3754 from Pseudomonas putida KT2440

    Beta-ketothiolase BktB
    SEED: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
    KEGG: acetyl-CoA C-acetyltransferase

    Rank Hit Name Description Conserved? Cofitness  
    1 PP_3753 Transcriptional regulator, AraC family 0.59 0.80
    2 PP_3755 3-hydroxybutyryl-CoA dehydrogenase 0.28 0.70
    3 PP_2790 Sigma-54 dependent sensory box protein 0.34 0.59
    4 PP_2791 4-hydroxypentanoyl-CoA kinase, subunit LvaA (from data) no 0.54
    5 PP_2333 GntR family transcriptional regulator 0.45 0.54
    6 PP_2794 Oxidoreductase, short chain dehydrogenase/reductase family 0.31 0.47
    7 PP_2335 methylcitrate synthase 0.36 0.47
    8 PP_2334 2-methylisocitrate lyase no 0.43
    9 PP_3756 TetR family transcriptional regulator 0.28 0.43
    10 PP_3286 DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA) no 0.40
    11 PP_4628 conserved protein of unknown function no 0.40
    12 PP_2793 Acyl-CoA dehydrogenase family protein no 0.38
    13 PP_3553 AMP-binding domain protein no 0.37
    14 PP_3554 Acyl-CoA dehydrogenase family protein no 0.36
    15 PP_2217 enoyl-CoA hydratase no 0.30
    16 PP_3552 Sensory box histidine kinase no 0.29
    17 PP_2337 aconitate isomerase 0.34 0.29
    18 PP_3925 conserved protein of unknown function no 0.29
    19 PP_4699 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.31 0.28
    20 PP_3122 acetoacetyl CoA-transferase (subunit A) no 0.28

    Or look for negative cofitness