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  • Top cofit genes for PP_2335 from Pseudomonas putida KT2440

    methylcitrate synthase
    SEED: 2-methylcitrate synthase (EC 2.3.3.5)
    KEGG: 2-methylcitrate synthase

    Rank Hit Name Description Conserved? Cofitness  
    1 PP_2334 2-methylisocitrate lyase 0.92 0.91
    2 PP_2333 GntR family transcriptional regulator 0.85 0.59
    3 PP_3753 Transcriptional regulator, AraC family no 0.50
    4 PP_3754 Beta-ketothiolase BktB 0.34 0.47
    5 PP_2337 aconitate isomerase 0.89 0.46
    6 PP_4628 conserved protein of unknown function 0.75 0.42
    7 PP_4667 methylmalonate-semialdehyde dehydrogenase 0.93 0.42
    8 PP_4666 3-hydroxyisobutyrate dehydrogenase 0.91 0.42
    9 PP_3925 conserved protein of unknown function no 0.42
    10 PP_3491 Enoly-coenzyme A hydratase/isomerase family protein 0.94 0.41
    11 PP_4668 Transcriptional regulator, LysR family 0.96 0.39
    12 PP_2217 enoyl-CoA hydratase 0.88 0.39
    13 PP_2213 putative acyl-CoA synthetase 0.55 0.39
    14 PP_2336 aconitate hydratase 1 0.92 0.38
    15 PP_4699 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.33 0.38
    16 PP_3755 3-hydroxybutyryl-CoA dehydrogenase no 0.35
    17 PP_3731 Transcriptional regulator, TetR family no 0.35
    18 PP_4404 dihydrolipoyl dehydrogenase component of branched-chain alpha-keto acid dehydrogenase complex 0.81 0.35
    19 PP_2868 Transcriptional regulator, Cro/CI family no 0.35
    20 PP_1941 conserved protein of unknown function no 0.35

    Or look for negative cofitness