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  • Top cofit genes for PP_2213 from Pseudomonas putida KT2440

    putative acyl-CoA synthetase
    SEED: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases
    KEGG: acetyl-CoA synthetase

    Rank Hit Name Description Conserved? Cofitness  
    1 PP_2216 short-chain acyl-CoA dehydrogenase 0.91 0.73
    2 PP_2215 acetyl-CoA acetyltransferase 0.91 0.69
    3 PP_2211 Transcriptional regulator, AraC family 0.91 0.69
    4 PP_2214 3-hydroxyacyl-CoA dehydrogenase type-2 0.77 0.54
    5 PP_2217 enoyl-CoA hydratase 0.56 0.45
    6 PP_2334 2-methylisocitrate lyase 0.67 0.40
    7 PP_2335 methylcitrate synthase 0.55 0.39
    8 PP_3756 TetR family transcriptional regulator 0.26 0.34
    9 PP_2333 GntR family transcriptional regulator 0.29 0.30
    10 PP_4404 dihydrolipoyl dehydrogenase component of branched-chain alpha-keto acid dehydrogenase complex 0.76 0.29
    11 PP_4403 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.62 0.29
    12 PP_4401 branched-chain alpha-keto acid dehydrogenase complex, alpha subunit 0.62 0.28
    13 PP_4400 Bkd operon transcriptional regulator 0.57 0.26
    14 PP_3491 Enoly-coenzyme A hydratase/isomerase family protein 0.30 0.25
    15 PP_4402 branched-chain alpha-keto acid dehydrogenase complex, beta subunit 0.59 0.24
    16 PP_2336 aconitate hydratase 1 0.45 0.22
    17 PP_2337 aconitate isomerase 0.49 0.21
    18 PP_3754 Beta-ketothiolase BktB 0.44 0.21
    19 PP_3755 3-hydroxybutyryl-CoA dehydrogenase 0.29 0.20
    20 PP_3510 conserved protein of unknown function no 0.19

    Or look for negative cofitness