Top cofit genes for HEPCGN_25650 from Escherichia coli ECOR38

pyrF: orotidine-5'-phosphate decarboxylase
SEED: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)
KEGG: orotidine-5'-phosphate decarboxylase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	HEPCGN_10060	pyrB	aspartate carbamoyltransferase	0.98	0.98
2	HEPCGN_14420	pyrE	Orotate phosphoribosyltransferase	0.98	0.98
3	HEPCGN_23760	pyrC	dihydroorotase	0.99	0.97
4	HEPCGN_25525	trpCF	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	0.94	0.97
5	HEPCGN_08925	carB	carbamoyl-phosphate synthase large subunit	1.00	0.97
6	HEPCGN_08930	carA	carbamoyl phosphate synthase small subunit	0.95	0.96
7	HEPCGN_25535	trpE	anthranilate synthase component I	0.93	0.95
8	HEPCGN_08820	pdxA	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	0.95	0.94
9	HEPCGN_25515	trpA	tryptophan synthase subunit alpha	0.94	0.94
10	HEPCGN_25530	trpD	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	0.92	0.93
11	HEPCGN_20615	purL	phosphoribosylformylglycinamidine synthase	0.97	0.93
12	HEPCGN_25520	trpB	tryptophan synthase subunit beta	0.94	0.93
13	HEPCGN_11955	purD	Phosphoribosylamine--glycine ligase	0.96	0.92
14	HEPCGN_21910	purF	amidophosphoribosyltransferase	0.96	0.91
15	HEPCGN_23225	pyrD	quinone-dependent dihydroorotate dehydrogenase	0.99	0.91
16	HEPCGN_21865	pdxB	4-phosphoerythronate dehydrogenase PdxB	0.94	0.91
17	HEPCGN_06475	purE	N5-carboxyaminoimidazole ribonucleotide mutase	0.95	0.90
18	HEPCGN_10460	purA	adenylosuccinate synthase	0.91	0.90
19	HEPCGN_23030	serC	3-phosphoserine/phosphohydroxythreonine transaminase	0.85	0.90
20	HEPCGN_12010	thiC	phosphomethylpyrimidine synthase ThiC	0.91	0.89

Or look for negative cofitness