Top cofit genes for HEPCGN_21820 from Escherichia coli ECOR38

aroC: chorismate synthase
SEED: Chorismate synthase (EC 4.2.3.5)
KEGG: chorismate synthase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	HEPCGN_03205	hisH	imidazole glycerol phosphate synthase subunit HisH	0.92	0.96
2	HEPCGN_23035	aroA	3-phosphoshikimate 1-carboxyvinyltransferase	0.98	0.96
3	HEPCGN_03225	hisG	ATP phosphoribosyltransferase	0.94	0.96
4	HEPCGN_12230	argC	N-acetyl-gamma-glutamyl-phosphate reductase	0.96	0.96
5	HEPCGN_13335	ilvC	ketol-acid reductoisomerase	0.96	0.96
6	HEPCGN_03190	hisIE	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	0.95	0.95
7	HEPCGN_20345	pheA	bifunctional chorismate mutase/prephenate dehydratase	0.98	0.95
8	HEPCGN_09200	serB	phosphoserine phosphatase	0.96	0.95
9	HEPCGN_08705	leuC1	3-isopropylmalate dehydratase large subunit 1	0.97	0.95
10	HEPCGN_08695		2-isopropylmalate synthase	0.98	0.95
11	HEPCGN_12240	ppc	phosphoenolpyruvate carboxylase	0.95	0.95
12	HEPCGN_19625	cysN	sulfate adenylyltransferase subunit CysN	0.96	0.95
13	HEPCGN_19620	cysD	sulfate adenylyltransferase subunit CysD	0.96	0.95
14	HEPCGN_07780	proB	Glutamate 5-kinase	0.92	0.94
15	HEPCGN_13350	ilvD	dihydroxy-acid dehydratase	0.96	0.94
16	HEPCGN_13340	ilvY	HTH-type transcriptional activator IlvY	0.96	0.94
17	HEPCGN_19570	lysR	DNA-binding transcriptional regulator LysR	0.95	0.94
18	HEPCGN_03220	hisD	Histidinol dehydrogenase	0.95	0.94
19	HEPCGN_19565	lysA	diaminopimelate decarboxylase	0.96	0.94
20	HEPCGN_03215	hisC	histidinol-phosphate transaminase	0.93	0.94

Or look for negative cofitness