Top cofit genes for GFF5461 from Variovorax sp. SCN45

2-dehydrotetronate isomerase (EC 5.3.1.35)
SEED: Hydroxypyruvate isomerase (EC 5.3.1.22)
KEGG: hydroxypyruvate isomerase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	GFF5218		ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines)	no	0.70
2	GFF423		Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	no	0.59
3	GFF5769		Chemotaxis response - phosphatase CheZ	0.68	0.59
4	GFF580		Rhodanese domain protein UPF0176, Betaproteobacterial subgroup	no	0.57
5	GFF2230		3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6)	no	0.56
6	GFF5453		Alkaline phosphatase (EC 3.1.3.1)	no	0.56
7	GFF570		3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25)	0.17	0.56
8	GFF1364		diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)	no	0.56
9	GFF3425		no description	no	0.55
10	GFF1412		Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-)	no	0.55
11	GFF4571		Acyl-CoA dehydrogenase family protein	no	0.54
12	GFF5815		Uncharacterized MFS-type transporter	no	0.53
13	GFF604		Tricarballylate utilization protein, TcuB	no	0.53
14	GFF2164		Transcriptional regulator, IclR family	0.16	0.53
15	GFF7145		Transcriptional regulator, GntR family	no	0.52
16	GFF7389		Cyclohexanone monooxygenase (EC 1.14.13.22)	no	0.52
17	GFF2422		Polysaccharide deacetylase	no	0.51
18	GFF3155		Gluconolactonase (EC 3.1.1.17)	no	0.51
19	GFF963		Oligopeptidase A (EC 3.4.24.70)	0.21	0.51
20	GFF1532		hypothetical protein	no	0.51

Or look for negative cofitness