Top cofit genes for GFF4432 from Variovorax sp. SCN45

Two-component system response regulator protein
SEED: Sigma-54 dependent transcriptional regulator
KEGG: two-component system, NtrC family, response regulator PilR

Rank Hit Name Description Conserved? Cofitness  
1 GFF993 Type IV pilus biogenesis protein PilF 0.93 0.99
2 GFF5418 Type IV fimbrial biogenesis protein PilY1 no 0.99
3 GFF5417 hypothetical protein no 0.98
4 GFF5419 Type IV pilus biogenesis protein PilE 0.97 0.98
5 GFF2509 Type IV fimbrial assembly protein PilC 0.98 0.98
6 GFF5416 Type IV fimbrial biogenesis protein PilW no 0.98
7 GFF5490 Uncharacterized protein with LysM domain, COG1652 0.98 0.98
8 GFF5319 Type IV pilus biogenesis protein PilM 0.99 0.98
9 GFF2510 Type IV fimbrial assembly, ATPase PilB 0.98 0.98
10 GFF5322 Type IV pilus biogenesis protein PilP 0.99 0.98
11 GFF5321 Type IV pilus biogenesis protein PilO 0.99 0.98
12 GFF5323 Type IV pilus biogenesis protein PilQ 0.98 0.98
13 GFF6075 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB 0.98 0.98
14 GFF3826 Response regulator receiver:LytTr DNA-binding region 0.97 0.98
15 GFF2508 Leader peptidase (Prepilin peptidase) (EC 3.4.23.43) / N-methyltransferase (EC 2.1.1.-) 0.98 0.98
16 GFF3068 FIG00538108: hypothetical protein 0.98 0.98
17 GFF5320 Type IV pilus biogenesis protein PilN 0.98 0.97
18 GFF5414 hypothetical protein no 0.97
19 GFF5415 Type IV fimbrial biogenesis protein PilV 0.97 0.97
20 GFF2519 FIG016425: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) 0.98 0.97

Or look for negative cofitness