Top cofit genes for GFF440 from Variovorax sp. SCN45

CobN-like chelatase BtuS for metalloporphyrine salvage
SEED: CobN component of cobalt chelatase involved in B12 biosynthesis
KEGG: cobaltochelatase CobN

Rank Hit Name Description Conserved? Cofitness  
1 GFF450 Outer membrane vitamin B12 receptor BtuB no 0.92
2 GFF7064 Glutamate--cysteine ligase (EC 6.3.2.2) no 0.90
3 GFF343 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) no 0.90
4 GFF931 Methylmalonyl-CoA mutase (EC 5.4.99.2) / B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) 0.29 0.90
5 GFF6305 Malate synthase G (EC 2.3.3.9) no 0.90
6 GFF4829 Isocitrate lyase (EC 4.1.3.1) no 0.90
7 GFF829 Aerobic cobaltochelatase CobN subunit (EC 6.6.1.2) no 0.90
8 GFF3583 AMP nucleosidase (EC 3.2.2.4) no 0.90
9 GFF6322 Glutathione synthetase (EC 6.3.2.3) no 0.90
10 GFF6191 Aldehyde dehydrogenase (EC 1.2.1.3) no 0.89
11 GFF1167 Predicted Lactate-responsive regulator, IclR family no 0.89
12 GFF7035 UspA no 0.89
13 GFF2818 Phosphoenolpyruvate synthase (EC 2.7.9.2) no 0.88
14 GFF1322 [Protein-PII] uridylyltransferase (EC 2.7.7.59) / [Protein-PII]-UMP uridylyl-removing enzyme no 0.88
15 GFF665 hypothetical protein no 0.88
16 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) no 0.88
17 GFF5332 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) no 0.87
18 GFF6150 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) no 0.87
19 GFF2843 Murein hydrolase activator NlpD no 0.87
20 GFF4803 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) no 0.87

Or look for negative cofitness