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Cofit
Protein
Homologs
Top cofit genes for GFF3975 from
Variovorax sp. SCN45
Metal-dependent hydrolase
SEED: conserved hypothetical protein
Rank
Hit
Name
Description
Conserved?
Cofitness
1
GFF2008
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
no
0.83
2
GFF2013
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
no
0.81
3
GFF6150
Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)
no
0.80
4
GFF5071
AmpG permease
no
0.80
5
GFF6381
ABC transporter, permease protein 1 (cluster 4, leucine/isoleucine/valine/benzoate) / ABC transporter, permease protein 2 (cluster 4, leucine/isoleucine/valine/benzoate)
no
0.79
6
GFF6325
Glutamate--cysteine ligase (EC 6.3.2.2), divergent, of Alpha- and Beta-proteobacteria type
no
0.78
7
GFF3583
AMP nucleosidase (EC 3.2.2.4)
0.28
0.78
8
GFF936
Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3)
no
0.78
9
GFF7035
UspA
no
0.77
10
GFF4492
Protein of unknown function DUF484
no
0.77
11
GFF1164
2-isopropylmalate synthase (EC 2.3.3.13)
no
0.77
12
GFF2498
Glutamate N-acetyltransferase (EC 2.3.1.35) @ N-acetylglutamate synthase (EC 2.3.1.1)
no
0.77
13
GFF2499
ATP/GTP-binding protein
no
0.77
14
GFF3943
Poly(A) polymerase (EC 2.7.7.19)
no
0.77
15
GFF2307
Heme O synthase, protoheme IX farnesyltransferase, COX10-CtaB
no
0.77
16
GFF7064
Glutamate--cysteine ligase (EC 6.3.2.2)
no
0.77
17
GFF343
Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
no
0.77
18
GFF903
Acetolactate synthase large subunit (EC 2.2.1.6)
no
0.76
19
GFF460
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
no
0.76
20
GFF6695
Ubiquinol-cytochrome C reductase, cytochrome B subunit (EC 1.10.2.2)
no
0.76
Or look for
negative cofitness