Top cofit genes for GFF2540 from Variovorax sp. SCN45

Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
SEED: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Rank Hit Name Description Conserved? Cofitness  
1 GFF4376 UPF0380 proteins YafZ and homologs 0.24 0.65
2 GFF5984 L-lactate dehydrogenase no 0.62
3 GFF699 ABC transporter, ATP-binding protein 2 (cluster 4, leucine/isoleucine/valine/benzoate) no 0.59
4 GFF1371 Fe-S protein, homolog of lactate dehydrogenase SO1521 no 0.59
5 GFF6928 Putative transmembrane protein no 0.58
6 GFF2190 Protocatechuate 3,4-dioxygenase beta chain (EC 1.13.11.3) no 0.58
7 GFF7250 Putative transposase InsK for insertion sequence element IS150 no 0.57
8 GFF7271 Transcriptional regulator, LacI family no 0.56
9 GFF2239 no description no 0.55
10 GFF3117 Beta-phosphoglucomutase (EC 5.4.2.6) no 0.55
11 GFF4945 probable GntR-family transcriptional regulator no 0.55
12 GFF1617 Phosphonate uptake and metabolism regulator, LysR-family no 0.55
13 GFF5788 FIG004556: membrane metalloprotease no 0.55
14 GFF3999 GMP reductase (EC 1.7.1.7) 0.21 0.55
15 GFF2740 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) no 0.55
16 GFF5675 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) no 0.55
17 GFF5511 FIG000875: Thioredoxin domain-containing protein EC-YbbN no 0.54
18 GFF5367 GTP cyclohydrolase 1 type 2 homolog YbgI no 0.53
19 GFF289 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 no 0.53
20 GFF5973 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) no 0.53

Or look for negative cofitness