Top cofit genes for GFF2023 from Variovorax sp. SCN45

Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
SEED: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
KEGG: hydroxymethylglutaryl-CoA lyase

Rank Hit Name Description Conserved? Cofitness  
1 GFF988 LSU rRNA pseudouridine(1911/1915/1917) synthase (EC 5.4.99.23) 0.85 0.69
2 GFF357 SOS-response repressor and protease LexA (EC 3.4.21.88) 0.63 0.67
3 GFF237 ABC-type branched-chain amino acid transport systems, periplasmic component 0.47 0.67
4 GFF232 Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18) no 0.63
5 GFF990 LSU rRNA pseudouridine(2605) synthase (EC 5.4.99.22) no 0.63
6 GFF6032 Branched-chain amino acid ABC transporter, permease protein LivM (TC 3.A.1.4.1) 0.54 0.60
7 GFF3496 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) no 0.60
8 GFF219 GTP-binding protein TypA/BipA 0.33 0.60
9 GFF3905 Aconitate hydratase 2 (EC 4.2.1.3) no 0.60
10 GFF6328 LPS-assembly lipoprotein LptE no 0.59
11 GFF2010 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) 0.93 0.59
12 GFF2616 no description no 0.59
13 GFF3649 C-type cytochrome biogenesis protein ResA (thioredoxin) no 0.58
14 GFF7289 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) @ S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) no 0.58
15 GFF344 no description no 0.58
16 GFF1159 Acetolactate synthase small subunit (EC 2.2.1.6) 0.42 0.58
17 GFF3960 3'-to-5' oligoribonuclease (orn) 0.24 0.58
18 GFF5673 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) 0.76 0.58
19 GFF4454 Exoribonuclease II (EC 3.1.13.1) no 0.57
20 GFF2343 ABC transporter, permease protein 2 (cluster 5, nickel/peptides/opines) no 0.57

Or look for negative cofitness