Top cofit genes for GFF1858 from Sphingobium sp. HT1-2

Precorrin-2 C(20)-methyltransferase (EC 2.1.1.130)
SEED: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
KEGG: precorrin-2/cobalt-factor-2 C20-methyltransferase

Rank Hit Name Description Conserved? Cofitness  
1 GFF3061 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) 0.92 0.84
2 GFF3495 hypothetical protein no 0.84
3 GFF1855 Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] (EC 2.1.1.132) 0.95 0.83
4 GFF3242 ATP phosphoribosyltransferase (EC 2.4.2.17) => HisGs 0.91 0.83
5 GFF1856 Precorrin-6A reductase (EC 1.3.1.54) 0.95 0.83
6 GFF1853 Precorrin-4 C(11)-methyltransferase (EC 2.1.1.133) 0.93 0.82
7 GFF1891 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.85 0.81
8 GFF3241 Histidinol dehydrogenase (EC 1.1.1.23) 0.92 0.81
9 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.95 0.81
10 GFF3439 Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3) no 0.80
11 GFF633 Homoserine dehydrogenase (EC 1.1.1.3) 0.49 0.80
12 GFF1857 Precorrin-3B C(17)-methyltransferase (EC 2.1.1.131) 0.94 0.80
13 GFF816 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) 0.93 0.80
14 GFF1860 Precorrin-3B synthase 0.97 0.80
15 GFF4267 IncF plasmid conjugative transfer protein TraD no 0.79
16 GFF3322 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) @ Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.91 0.79
17 GFF3534 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.63 0.78
18 GFF1859 Precorrin-8X methylmutase (EC 5.4.99.61) 0.94 0.78
19 GFF1851 Precorrin-6A synthase (deacetylating) (EC 2.1.1.152) 0.87 0.78
20 GFF1923 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) 0.26 0.78

Or look for negative cofitness