Top cofit genes for Echvi_4478 from Echinicola vietnamensis KMM 6221, DSM 17526

heavy metal efflux pump (cobalt-zinc-cadmium)
SEED: Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA

Rank	Hit	Name	Description	Conserved?	Cofitness
1	Echvi_4472		heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase	no	0.75
2	Echvi_4477		RND family efflux transporter, MFP subunit	0.87	0.68
3	Echvi_4473		Fe2+/Zn2+ uptake regulation proteins	0.64	0.68
4	Echvi_4476		Nitrogen regulatory protein PII	no	0.62
5	Echvi_4475		Divergent AAA domain.	no	0.60
6	Echvi_4118		hypothetical protein	no	0.52
7	Echvi_4474		hypothetical protein	no	0.45
8	Echvi_4567		Outer membrane receptor proteins, mostly Fe transport	no	0.42
9	Echvi_3302		hypothetical protein	no	0.39
10	Echvi_1174		Fe2+/Zn2+ uptake regulation proteins	no	0.36
11	Echvi_3952		NAD-dependent aldehyde dehydrogenases	no	0.36
12	Echvi_1993		Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	no	0.36
13	Echvi_1579		hypothetical protein	no	0.35
14	Echvi_2817		Na+/H+ antiporter NhaC	no	0.35
15	Echvi_3726		DNA-binding ferritin-like protein (oxidative damage protectant)	no	0.33
16	Echvi_1045		Transcriptional regulator	no	0.33
17	Echvi_3950		Glycine/D-amino acid oxidases (deaminating)	no	0.33
18	Echvi_0586		DNA-binding ferritin-like protein (oxidative damage protectant)	no	0.32
19	Echvi_0224		hypothetical protein	no	0.32
20	Echvi_4329		Outer membrane receptor proteins, mostly Fe transport	no	0.31

Or look for negative cofitness