Top cofit genes for EFB2_00454 from Escherichia fergusonii Becca

Siroheme synthase
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
KEGG: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	EFB2_01170		Flavodoxin FldP	no	0.59
2	EFB2_04681		hypothetical protein	no	0.56
3	EFB2_02362		Ion-translocating oxidoreductase complex subunit D	no	0.56
4	EFB2_04714		L-rhamnose isomerase	no	0.55
5	EFB2_00200		Glutaredoxin 3	no	0.55
6	EFB2_00763		Ubiquinone biosynthesis accessory factor UbiK	no	0.54
7	EFB2_04871		HTH-type transcriptional regulator HdfR	no	0.54
8	EFB2_04599		hypothetical protein	no	0.54
9	EFB2_00799		Alcohol dehydrogenase YqhD	no	0.53
10	EFB2_04706		Sensor histidine kinase CpxA	no	0.53
11	EFB2_03781		hypothetical protein	no	0.52
12	EFB2_01079		hypothetical protein	no	0.52
13	EFB2_00456		Nitrite reductase (NADH) small subunit	no	0.52
14	EFB2_04870		hypothetical protein	no	0.52
15	EFB2_00668		hypothetical protein	no	0.51
16	EFB2_00631		Intermembrane phospholipid transport system binding protein MlaC	no	0.51
17	EFB2_02845		Transcriptional regulatory protein PhoP	no	0.50
18	EFB2_01409		Outer membrane protein assembly factor BamC	no	0.50
19	EFB2_01514		Intermembrane phospholipid transport system lipoprotein MlaA	0.33	0.50
20	EFB2_03567		Inner membrane protein YbbJ	no	0.50

Or look for negative cofitness