Top cofit genes for ECD_03707 from Escherichia coli BL21

methionine biosynthesis regulon transcriptional regulator
SEED: Transcriptional activator MetR
KEGG: LysR family transcriptional regulator, regulator for metE and metH

Rank Hit Name Description Conserved? Cofitness  
1 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.99 0.90
2 ECD_03077 glutamate synthase, large subunit 0.95 0.85
3 ECD_02489 fused chorismate mutase T/prephenate dehydrogenase 0.99 0.84
4 ECD_03649 dihydroxyacid dehydratase 0.99 0.83
5 ECD_03078 glutamate synthase, 4Fe-4S protein, small subunit 0.95 0.83
6 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.99 0.82
7 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.98 0.82
8 ECD_00074 3-isopropylmalate dehydratase large subunit 0.98 0.80
9 ECD_03648 branched-chain amino acid aminotransferase 0.88 0.80
10 ECD_03650 l-threonine dehydratase, biosynthetic; also known as threonine deaminase 0.96 0.79
11 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.98 0.77
12 ECD_03845 argininosuccinate lyase 0.96 0.76
13 ECD_03842 acetylornithine deacetylase 0.89 0.75
14 ECD_03844 acetylglutamate kinase 0.95 0.73
15 ECD_03841 phosphoenolpyruvate carboxylase 0.99 0.73
16 ECD_03843 N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding 0.95 0.72
17 ECD_00004 L-threonine synthase 0.96 0.71
18 ECD_00076 2-isopropylmalate synthase 0.96 0.71
19 ECD_03038 argininosuccinate synthetase 0.92 0.70
20 ECD_00003 homoserine kinase 0.96 0.69

Or look for negative cofitness