Top cofit genes for ECD_03677 from Escherichia coli BL21

putative protoheme IX synthesis protein
SEED: Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)
KEGG: HemY protein

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_03259		putative transcriptional accessory protein	0.71	0.71
2	ECD_03243		DNA catabolic putative fimbrial transporter	no	0.68
3	ECD_02661		cysteine sulfinate desulfinase	0.28	0.68
4	ECD_03624		16S rRNA m(7)G527 methyltransferase, SAM-dependent; glucose-inhibited cell-division protein	0.73	0.66
5	ECD_02578		hydrogenase maturation protein	0.68	0.66
6	ECD_02302		nucleoside (except guanosine) transporter	0.78	0.65
7	ECD_02938		G/U mismatch-specific DNA glycosylase; xanthine DNA glycosylase	no	0.63
8	ECD_02663		tRNA threonylcarbamoyladenosine dehydratase; sulfur acceptor for CsdA	0.27	0.63
9	ECD_02706		D-stereospecific phenylhydantoinase	no	0.63
10	ECD_03500		ribonuclease PH	0.63	0.63
11	ECD_02637		DUF446 family protein	no	0.63
12	ECD_04260		purine nucleoside phosphorylase 1; nicotinamide 1-beta-D-riboside phosphorylase	0.66	0.62
13	ECD_03250		putative RcsCDB-response attenuator, inner membrane protein	no	0.62
14	ECD_03799		inhibitor of the cpx response; periplasmic adaptor protein	0.48	0.62
15	ECD_02736		glycine cleavage complex lipoylprotein	0.46	0.62
16	ECD_03660		rho operon leader peptide	no	0.61
17	ECD_03691		DUF2233 family protein	no	0.61
18	ECD_02657		23S rRNA C2498 2'-O-ribose methyltransferase, SAM-dependent	no	0.61
19	ECD_02409		dual specificity 23S rRNA m(2)A2503, tRNA m(2)A37 methyltransferase, SAM-dependent	0.34	0.61
20	ECD_03246		DNA catabolic putative fimbrial assembly protein	no	0.60

Or look for negative cofitness