Top cofit genes for ECD_03314 from Escherichia coli BL21

16S rRNA m(2)G966 methyltransferase, SAM-dependent
KEGG: ribosomal RNA small subunit methyltransferase D

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_02861		putative ATP-binding protein	no	0.73
2	ECD_00165		uridylyltransferase	0.42	0.72
3	ECD_02631		hybrid sensory histidine kinase, in two-component regulatory system with UvrY	0.77	0.72
4	ECD_03740		potassium transporter	0.82	0.69
5	ECD_02750		methylmalonyl-CoA decarboxylase, biotin-independent	no	0.68
6	ECD_02731		hemolysin III family HylIII inner membrane protein	no	0.68
7	ECD_03426		transcriptional repressor for the yiaKLMNO-lyxK-sgbHUE operon	no	0.68
8	ECD_03345		dipeptide and tripeptide permease B	no	0.68
9	ECD_03455		mannitol-1-phosphate dehydrogenase, NAD-dependent	0.65	0.68
10	ECD_03342		phosphate transporter, low-affinity; tellurite importer	0.46	0.67
11	ECD_02620		putative kinase	no	0.67
12	ECD_03346		16S rRNA m(2)G1516 methyltransferase, SAM-dependent	0.61	0.66
13	ECD_02508		tmRNA-binding trans-translation protein	0.75	0.66
14	ECD_03579		putative lipoprotein	no	0.66
15	ECD_03850		tRNA m(5)U54 methyltransferase, SAM-dependent; tmRNA m(5)U341 methyltransferase	0.42	0.65
16	ECD_03488		UDP-glucose:(heptosyl)lipopolysaccharide alpha-1,3-glucosyltransferase; lipopolysaccharide core biosynthesis protein; lipopolysaccharide glucosyltransferase I	no	0.65
17	ECD_00361		Nrd regulon repressor	0.70	0.64
18	ECD_03657		guanosine pentaphosphatase/exopolyphosphatase	0.75	0.63
19	ECD_03363		transcriptional activator of gadA and gadBC; repressor of gadX	no	0.63
20	ECD_02755		mechanosensitive channel protein, small conductance	0.42	0.63

Or look for negative cofitness