Top cofit genes for ECD_03216 from Escherichia coli BL21

nitrite reductase, large subunit, NAD(P)H-binding
SEED: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
KEGG: nitrite reductase (NAD(P)H) large subunit

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_02409		dual specificity 23S rRNA m(2)A2503, tRNA m(2)A37 methyltransferase, SAM-dependent	0.27	0.71
2	ECD_01794		DUF2527 family heat-induced protein	0.42	0.65
3	ECD_00392		HU, DNA-binding transcriptional regulator, beta subunit	0.56	0.65
4	ECD_02423		isc operon transcriptional repressor; suf operon transcriptional activator; oxidative stress- and iron starvation-inducible; autorepressor	0.36	0.65
5	ECD_02997		tagatose 6-phosphate aldolase 1, kbaZ subunit	no	0.64
6	ECD_03016		DnaA initiator-associating factor for replication initiation	0.33	0.64
7	ECD_03259		putative transcriptional accessory protein	0.41	0.62
8	ECD_02424		tRNA mC32,mU32 2'-O-methyltransferase, SAM-dependent	no	0.62
9	ECD_02244		putative semialdehyde dehydrogenase	no	0.62
10	ECD_03624		16S rRNA m(7)G527 methyltransferase, SAM-dependent; glucose-inhibited cell-division protein	no	0.61
11	ECD_02817		KpsU protein	no	0.61
12	ECD_02642		L-serine dehydratase 2	no	0.60
13	ECD_02550		nicotinamide-nucleotide amidohydrolase; NMN amidohydrolase	no	0.60
14	ECD_00061		RNA polymerase remodeling/recycling factor ATPase; RNA polymerase-associated, ATP-dependent RNA translocase	0.55	0.60
15	ECD_03646		acetolactate synthase II, valine insensitive, large subunit	0.42	0.60
16	ECD_00142		poly(A) polymerase	no	0.60
17	ECD_03200		FKBP-type peptidyl prolyl cis-trans isomerase (rotamase)	0.71	0.60
18	ECD_02661		cysteine sulfinate desulfinase	no	0.60
19	ECD_01081		uncharacterized protein	no	0.60
20	ECD_r00015		23S ribosomal RNA	no	0.59

Or look for negative cofitness