Top cofit genes for ECD_03077 from Escherichia coli BL21

glutamate synthase, large subunit
SEED: Glutamate synthase [NADPH] large chain (EC 1.4.1.13)

Rank Hit Name Description Conserved? Cofitness  
1 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.90 0.91
2 ECD_03649 dihydroxyacid dehydratase 0.99 0.90
3 ECD_03078 glutamate synthase, 4Fe-4S protein, small subunit 1.00 0.89
4 ECD_02489 fused chorismate mutase T/prephenate dehydrogenase 0.92 0.86
5 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.99 0.85
6 ECD_03707 methionine biosynthesis regulon transcriptional regulator 0.95 0.85
7 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.99 0.84
8 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.99 0.83
9 ECD_00074 3-isopropylmalate dehydratase large subunit 0.99 0.82
10 ECD_03650 l-threonine dehydratase, biosynthetic; also known as threonine deaminase 0.98 0.82
11 ECD_03843 N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding 0.99 0.81
12 ECD_03648 branched-chain amino acid aminotransferase 0.97 0.81
13 ECD_03842 acetylornithine deacetylase 0.93 0.81
14 ECD_03038 argininosuccinate synthetase 0.99 0.81
15 ECD_00003 homoserine kinase 0.97 0.80
16 ECD_00961 outer membrane protein A (3a no 0.80
17 ECD_03845 argininosuccinate lyase 1.00 0.80
18 ECD_03841 phosphoenolpyruvate carboxylase 0.98 0.79
19 ECD_02666 amino acid N-acetyltransferase and inactive acetylglutamate kinase 0.99 0.78
20 ECD_00076 2-isopropylmalate synthase 0.99 0.76

Or look for negative cofitness