Top cofit genes for ECD_02776 from Escherichia coli BL21

16S rRNA m(3)U1498 methyltransferase, SAM-dependent
SEED: Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-)
KEGG: ribosomal RNA small subunit methyltransferase E

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_01082		23S rRNA pseudouridine(955,2504,2580) synthase	0.49	0.87
2	ECD_02741		UPF0149 family protein	0.62	0.78
3	ECD_02526		alanine exporter, alanine-inducible, stress-responsive	no	0.78
4	ECD_02484		23S rRNA pseudouridine(1911,1915,1917) synthase	0.81	0.78
5	ECD_01489		transcriptional repressor of multiple antibiotic resistance	0.40	0.77
6	ECD_00371		tRNA s(4)U8 sulfurtransferase	0.74	0.77
7	ECD_02523		tributyltin-inducible repressor of ygaVP	0.70	0.76
8	ECD_03118		tRNA-dihydrouridine synthase B	0.57	0.75
9	ECD_01770		D-malate oxidase, NAD-dependent; putative tartrate dehydrogenase	no	0.74
10	ECD_02255		N5-glutamine methyltransferase	0.60	0.73
11	ECD_01263		ribonuclease II	0.63	0.73
12	ECD_01276		repressor for the divergent puu operons, putrescine inducible	0.41	0.72
13	ECD_02559		anaerobic nitric oxide reductase DNA-binding transcriptional activator	0.54	0.71
14	ECD_00412		Hha toxicity attenuator; conjugation-related protein	no	0.70
15	ECD_02539		transcriptional repressor of microcin B17 synthesis and multidrug efflux	no	0.70
16	ECD_02530		NrdEF cluster assembly flavodoxin	no	0.70
17	ECD_01487		phage N15 gp48-like protein	no	0.70
18	ECD_03033		tRNA pseudouridine synthase B: tRNA pseudouridine(55) synthase and putative tmRNA pseudouridine(342) synthase	0.88	0.70
19	ECD_02790		tRNA m(7)G46 methyltransferase, SAM-dependent	0.67	0.68
20	ECD_04342		hypothetical protein	no	0.68

Or look for negative cofitness