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  • Top cofit genes for ECD_02687 from Escherichia coli BL21

    transcriptional activator of lysA; autorepressor
    SEED: Transcriptional activator protein LysR

    Rank Hit Name Description Conserved? Cofitness  
    1 ECD_02744 D-3-phosphoglycerate dehydrogenase 0.98 0.81
    2 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.99 0.77
    3 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.98 0.76
    4 ECD_02881 cystathionine beta-lyase, PLP-dependent 0.98 0.76
    5 ECD_00240 gamma-glutamylphosphate reductase 0.99 0.76
    6 ECD_04264 3-phosphoserine phosphatase 0.99 0.76
    7 ECD_00003 homoserine kinase 0.98 0.76
    8 ECD_03844 acetylglutamate kinase 0.99 0.75
    9 ECD_03038 argininosuccinate synthetase 0.98 0.75
    10 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.98 0.74
    11 ECD_02600 adenosine 5'-phosphosulfate kinase 0.98 0.74
    12 ECD_01923 histidinol-phosphate aminotransferase 0.97 0.74
    13 ECD_03845 argininosuccinate lyase 0.99 0.74
    14 ECD_03707 methionine biosynthesis regulon transcriptional regulator 0.98 0.73
    15 ECD_03648 branched-chain amino acid aminotransferase 0.99 0.73
    16 ECD_02686 diaminopimelate decarboxylase, PLP-binding 0.98 0.73
    17 ECD_00004 L-threonine synthase 0.98 0.72
    18 ECD_04120 ornithine carbamoyltransferase 1 0.97 0.72
    19 ECD_00239 gamma-glutamate kinase 0.98 0.72
    20 ECD_00074 3-isopropylmalate dehydratase large subunit 0.97 0.72

    Or look for negative cofitness