Top cofit genes for ECD_02622 from Escherichia coli BL21

7-carboxy-7-deazaguanine synthase; queosine biosynthesis
SEED: Queuosine Biosynthesis QueE Radical SAM
KEGG: queuosine biosynthesis protein QueE

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_03123		cytoplasmic membrane lipoprotein	no	0.71
2	ECD_02603		aminopeptidase in alkaline phosphatase isozyme conversion	no	0.70
3	ECD_02611		putative oxidoreductase	no	0.68
4	ECD_00192		putative lipoprotein	no	0.65
5	ECD_02586		putative dehydrogenase	0.29	0.65
6	ECD_02819		KpsS protein	no	0.62
7	ECD_00128		putative PTS Enzyme IIA	no	0.62
8	ECD_03142		alternate ribosome-rescue factor A	no	0.62
9	ECD_00129		putative polysaccharide deacetylase lipoprotein	no	0.62
10	ECD_03127		putative amino acid ABC transporter permease	0.49	0.61
11	ECD_01349		pyruvate-flavodoxin oxidoreductase	0.26	0.60
12	ECD_00201		LysR family putative transcriptional regulator	no	0.60
13	ECD_04072		putative oxidoreductase	no	0.60
14	ECD_02652		hypothetical protein	no	0.60
15	ECD_02195		RNase BN, tRNA processing enzyme	no	0.59
16	ECD_03817		peptidase component of the HslUV protease	0.37	0.59
17	ECD_02366		elongator methionine tRNA (ac4C34) acetyltransferase	no	0.58
18	ECD_00495		inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; UPF0098 family secreted protein	no	0.58
19	ECD_00542		weak gamma-glutamyl:cysteine ligase	no	0.57
20	ECD_04018		entericidin A membrane lipoprotein, antidote entericidin B	no	0.56

Or look for negative cofitness