Top cofit genes for ECD_02291 from Escherichia coli BL21

response regulator activating yhjX; pyruvate-responsive YpdAB two-component system
SEED: Hypothetical response regulatory protein ypdB
KEGG: two-component system, LytT family, response regulator

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_03189		periplasmic endochitinase	no	0.65
2	ECD_00929		murein L,D-transpeptidase	no	0.63
3	ECD_00119		S-adenosylmethionine decarboxylase	0.34	0.62
4	ECD_00408		putative membrane-anchored cyclic-di-GMP phosphodiesterase	no	0.61
5	ECD_03604		carbohydrate-specific outer membrane porin, cryptic	0.41	0.60
6	ECD_01223		cardiolipin synthase 1	0.94	0.60
7	ECD_02751		propionyl-CoA:succinate CoA transferase	no	0.60
8	ECD_03128		putative amino acid ABC transporter permease	no	0.60
9	ECD_02395		cyclic-di-GMP phosphodiesterase, anaerobic	no	0.58
10	ECD_00296		thiogalactoside acetyltransferase	no	0.58
11	ECD_01604		dipeptide and tripeptide permease A	0.42	0.58
12	ECD_02235		lysine/arginine/ornithine transporter subunit	no	0.58
13	ECD_02916		putative outer membrane usher protein	0.47	0.57
14	ECD_03591		tryptophanase leader peptide	no	0.57
15	ECD_03747		DUF945 family protein	no	0.57
16	ECD_02223		putative inner membrane transporter; C4-dicarboxylate anaerobic carrier family protein	no	0.56
17	ECD_04085		2':3'-cyclic-nucleotide 2'-phosphodiesterase	no	0.56
18	ECD_03127		putative amino acid ABC transporter permease	no	0.56
19	ECD_02319		uncharacterized protein	no	0.55
20	ECD_00860		putrescine ABC transporter ATPase	no	0.55

Or look for negative cofitness