Top cofit genes for ECD_00971 from Escherichia coli BL21

23S rRNA m(5)C1962 methyltransferase, SAM-dependent
SEED: LSU m5C1962 methyltransferase RlmI
KEGG: ribosomal RNA large subunit methyltransferase I

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_01079		flagellar hook-filament junction protein	no	0.63
2	ECD_02383		hydrogenase-4 transcriptional activator	0.46	0.62
3	ECD_02519		gamma-aminobutyrate transporter	no	0.62
4	ECD_02720		uric acid permease	no	0.62
5	ECD_01077		flagellar rod assembly protein and murein hydrolase; flagellum-specific muramidase	0.68	0.60
6	ECD_00376		hypothetical protein	no	0.60
7	ECD_00623		glutamate/aspartate periplasmic binding protein	0.35	0.60
8	ECD_02493		putative membrane-anchored diguanylate cyclase	0.51	0.60
9	ECD_04042		HflB protease modulator specific for phage lambda cII repressor	no	0.60
10	ECD_01604		dipeptide and tripeptide permease A	0.18	0.58
11	ECD_00691		alpha-mannosidase	no	0.58
12	ECD_00281		uncharacterized protein	0.45	0.58
13	ECD_03127		putative amino acid ABC transporter permease	0.47	0.57
14	ECD_03592		tryptophanase/L-cysteine desulfhydrase, PLP-dependent	no	0.57
15	ECD_01931		6-phosphogluconate dehydrogenase, decarboxylating	0.36	0.57
16	ECD_03761		putative sulfoquinovose importer	0.54	0.57
17	ECD_04130		transcriptional repressor, 5-gluconate-binding	no	0.56
18	ECD_00297		lactose permease	0.47	0.56
19	ECD_00325		microcin Bac7 uptake protein; outer membrane surface-exposed lipoprotein	no	0.56
20	ECD_02147		fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein	0.42	0.56

Or look for negative cofitness