Top cofit genes for ECD_00652 from Escherichia coli BL21

fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein
SEED: Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)
KEGG: two-component system, OmpR family, sensor histidine kinase KdpD

Rank Hit Name Description Conserved? Cofitness  
1 ECD_00456 glyoxylate-inducible transcriptional repressor of all and gcl operons no 0.64
2 ECD_02594 broad specificity 5'(3')-nucleotidase and polyphosphatase 0.37 0.62
3 ECD_00632 UMP phosphatase 0.32 0.61
4 ECD_01435 putative DNA-binding transcriptional regulator no 0.61
5 ECD_01703 phospho-chitobiase; general 6-phospho-beta-glucosidase activity no 0.60
6 ECD_03200 FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) no 0.60
7 ECD_01713 succinylglutamate desuccinylase no 0.59
8 ECD_00443 DnaK co-chaperone, thioredoxin-like protein 0.17 0.59
9 ECD_02591 RNA polymerase, sigma S (sigma 38) factor 0.32 0.59
10 ECD_01619 transcriptional repressor for the nemRA-gloA operon, quinone-, glyoxal-, and HOCl-activated 0.33 0.58
11 ECD_04089 UPF0053 family inner membrane protein 0.47 0.58
12 ECD_00606 ribosomal silencing factor no 0.57
13 ECD_00346 exonuclease, dsDNA, ATP-dependent no 0.57
14 ECD_01875 tyrosine transporter no 0.57
15 ECD_02371 transcriptional repressor, regulatory protein accessory to GcvA 0.68 0.57
16 ECD_00111 aromatic amino acid transporter no 0.57
17 ECD_01929 regulator of length of O-antigen component of lipopolysaccharide chains no 0.57
18 ECD_01281 regulatory protein for phage-shock-protein operon no 0.56
19 ECD_04299 Mn(2)-response protein, MntR-repressed no 0.56
20 ECD_00147 putative ATP-dependent helicase 0.48 0.56

Or look for negative cofitness