Top cofit genes for ECD_00643 from Escherichia coli BL21

acyl-CoA esterase
SEED: Esterase ybfF (EC 3.1.-.-)
KEGG:

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_02085		lysine transporter	0.55	0.74
2	ECD_01082		23S rRNA pseudouridine(955,2504,2580) synthase	0.64	0.74
3	ECD_02727		flavodoxin 2	0.62	0.73
4	ECD_01276		repressor for the divergent puu operons, putrescine inducible	0.51	0.73
5	ECD_01770		D-malate oxidase, NAD-dependent; putative tartrate dehydrogenase	no	0.71
6	ECD_01160		oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I	0.33	0.70
7	ECD_02208		NADH:ubiquinone oxidoreductase, chain G	0.52	0.69
8	ECD_02790		tRNA m(7)G46 methyltransferase, SAM-dependent	0.43	0.69
9	ECD_02767		agmatinase	0.51	0.69
10	ECD_00456		glyoxylate-inducible transcriptional repressor of all and gcl operons	no	0.69
11	ECD_02758		D-erythrose 4-phosphate dehydrogenase	0.33	0.68
12	ECD_02672		DUF2509 family protein	no	0.67
13	ECD_00069		thiamine/thiamine pyrophosphate ABC transporter permease	no	0.67
14	ECD_04058		transcriptional repressor for the L-ascorbate utilization divergent operon	0.42	0.67
15	ECD_03266		Fe/S biogenesis protein, putative scaffold/chaperone protein	0.41	0.66
16	ECD_03288		gluconate kinase 2	no	0.66
17	ECD_01826		myristoyl-acyl carrier protein (ACP)-dependent acyltransferase	no	0.66
18	ECD_02585		DeoR family putative transcriptional regulator	0.35	0.66
19	ECD_00415		transcriptional repressor	no	0.65
20	ECD_02202		NADH:ubiquinone oxidoreductase, membrane subunit M	0.56	0.65

Or look for negative cofitness