Top cofit genes for ECD_00531 from Escherichia coli BL21

copper-sensing histidine kinase in two-component regulatory system with CusR
KEGG: two-component system, OmpR family, heavy metal sensor histidine kinase CusS

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_00124		hypoxanthine phosphoribosyltransferase	no	0.66
2	ECD_00898		dimethyl sulfoxide reductase, anaerobic, subunit A	no	0.63
3	ECD_01755		putative diguanylate cyclase	no	0.63
4	ECD_02618		putative SDR family oxidoreductase	no	0.63
5	ECD_02111		uncharacterized protein	0.36	0.63
6	ECD_03865		stationary phase growth adaptation protein	no	0.62
7	ECD_02527		uncharacterized protein	0.65	0.61
8	ECD_00790		putative pyruvate formate lyase	no	0.61
9	ECD_03353		hypothetical protein	0.51	0.60
10	ECD_02947		putative transporter	no	0.60
11	ECD_02519		gamma-aminobutyrate transporter	0.55	0.60
12	ECD_00393		periplasmic folding chaperone, has an inactive PPIase domain	0.30	0.60
13	ECD_00974		Modulator of FtsH protease, inner membrane protein	0.33	0.60
14	ECD_00228		mRNA interferase toxin of the YafO-YafN toxin-antitoxin system	no	0.60
15	ECD_03185		general secretory pathway component, cryptic	no	0.59
16	ECD_00184		lysine decarboxylase 2, constitutive	no	0.58
17	ECD_00281		uncharacterized protein	no	0.58
18	ECD_03920		uncharacterized protein	no	0.58
19	ECD_03901		DUF940 family extracellular polysaccharide protein	0.56	0.57
20	ECD_02716		guanine deaminase	0.33	0.57

Or look for negative cofitness