Top cofit genes for ECD_00289 from Escherichia coli BL21

propionate--CoA ligase
SEED: Propionate--CoA ligase (EC 6.2.1.17)
KEGG: propionyl-CoA synthetase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_03866		tyrosine lyase, involved in thiamine-thiazole moiety synthesis	no	0.51
2	ECD_02342		reactivating factor for ethanolamine ammonia lyase	0.46	0.51
3	ECD_03783		putative peptidase	0.19	0.47
4	ECD_04254		putative DNase	0.48	0.47
5	ECD_00203		putative S-adenosyl-L-methionine-dependent methyltransferase	no	0.47
6	ECD_00649		ornithine decarboxylase isozyme, inducible	no	0.47
7	ECD_04216		endonuclease R Type I restriction enzyme	0.23	0.45
8	ECD_03302		sn-glycerol-3-phosphate ABC transporter periplasmic binding protein	0.55	0.44
9	ECD_01966		colanic acid production tyrosine-protein kinase; autokinase; Ugd phosphorylase	no	0.44
10	ECD_02684		fused 2-acylglycerophospho-ethanolamine acyl transferase/acyl-acyl carrier protein synthetase	no	0.44
11	ECD_02148		acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit	0.41	0.44
12	ECD_04042		HflB protease modulator specific for phage lambda cII repressor	0.81	0.43
13	ECD_02246		putative flagella assembly protein	no	0.43
14	ECD_03499		orotate phosphoribosyltransferase	no	0.43
15	ECD_04189		minor component of type 1 fimbriae	no	0.43
16	ECD_04212		5-methylcytosine-specific restriction enzyme McrBC, subunit McrB	no	0.42
17	ECD_02055		inner membrane putative sensory kinase in two-component system with YehT	0.45	0.42
18	ECD_00968		UPF0319 family protein	no	0.41
19	ECD_04085		2':3'-cyclic-nucleotide 2'-phosphodiesterase	no	0.41
20	ECD_03513		putative inner membrane-anchored periplasmic AsmA family protein	no	0.41

Or look for negative cofitness