Top cofit genes for ECD_00146 from Escherichia coli BL21

2'-5' RNA ligase
SEED: 2'-5' RNA ligase
KEGG: 2'-5' RNA ligase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	ECD_01875		tyrosine transporter	no	0.75
2	ECD_02482		protein disaggregation chaperone	no	0.74
3	ECD_02661		cysteine sulfinate desulfinase	no	0.74
4	ECD_00147		putative ATP-dependent helicase	0.80	0.74
5	ECD_02244		putative semialdehyde dehydrogenase	no	0.73
6	ECD_02021		D-tagatose 1,6-bisphosphate aldolase 2, subunit	no	0.73
7	ECD_01619		transcriptional repressor for the nemRA-gloA operon, quinone-, glyoxal-, and HOCl-activated	0.46	0.73
8	ECD_01929		regulator of length of O-antigen component of lipopolysaccharide chains	no	0.72
9	ECD_01164		D-amino acid dehydrogenase	no	0.72
10	ECD_01719		TVP38/TMEM64 family inner membrane protein	no	0.71
11	ECD_01625		murein DD-endopeptidase, space-maker hydrolase	no	0.71
12	ECD_00007		putative transporter	0.26	0.71
13	ECD_02086		putative DNA-binding transcriptional regulator	no	0.71
14	ECD_t00008		tRNA-Gln	no	0.71
15	ECD_02018		galactitol-specific enzyme IIC component of PTS	0.25	0.70
16	ECD_02627		mRNA interferase toxin, antitoxin is MazE	no	0.69
17	ECD_01121		spermidine/putrescine ABC transporter periplasmic binding protein	no	0.69
18	ECD_00901		putative isochorismatase family hydrolase	0.24	0.69
19	ECD_01492		cysteine and O-acetyl-L-serine efflux system	0.46	0.68
20	ECD_03799		inhibitor of the cpx response; periplasmic adaptor protein	0.28	0.68

Or look for negative cofitness