Top cofit genes for BNILDI_02540 from Escherichia coli ECRC62

cysG: siroheme synthase CysG
SEED: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
KEGG: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase

Rank Hit Name Description Conserved? Cofitness  
1 BNILDI_10740 cysI assimilatory sulfite reductase (NADPH) hemoprotein subunit 0.98 0.98
2 BNILDI_05070 metR HTH-type transcriptional regulator MetR 0.98 0.97
3 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 0.97
4 BNILDI_08550 2-isopropylmalate synthase 0.98 0.97
5 BNILDI_14715 hisF Imidazole glycerol phosphate synthase subunit HisF 0.99 0.97
6 BNILDI_11705 pheA bifunctional chorismate mutase/prephenate dehydratase 0.97 0.97
7 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.99 0.97
8 BNILDI_10805 cysD sulfate adenylyltransferase subunit CysD 0.99 0.96
9 BNILDI_04745 ilvE branched-chain-amino-acid transaminase 0.97 0.96
10 BNILDI_10735 cysJ NADPH-dependent assimilatory sulfite reductase flavoprotein subunit 0.99 0.96
11 BNILDI_00780 metC cystathionine beta-lyase 0.98 0.96
12 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 1.00 0.96
13 BNILDI_14740 hisD Histidinol dehydrogenase 0.99 0.96
14 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.96 0.96
15 BNILDI_04760 ilvY HTH-type transcriptional activator IlvY 0.99 0.96
16 BNILDI_10810 cysN sulfate adenylyltransferase subunit CysN 0.99 0.96
17 BNILDI_08545 leuA 2-isopropylmalate synthase 0.99 0.95
18 BNILDI_14725 hisH imidazole glycerol phosphate synthase subunit HisH 0.98 0.95
19 BNILDI_07225 cysQ 3'(2'),5'-bisphosphate nucleotidase CysQ 0.95 0.95
20 BNILDI_14720 hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase 0.98 0.95

Or look for negative cofitness