Top cofit genes for b4480 from Escherichia coli BW25113

hdfR: transcriptional regulator HdfR (NCBI)
SEED: HTH-type transcriptional regulator hdfR

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3764	yifE	hypothetical protein (NCBI)	0.98	0.94
2	b3765	yifB	predicted bifunctional enzyme and transcriptional regulator (RefSeq)	0.86	0.60
3	b2289	lrhA	DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI)	0.79	0.58
4	b0145	dksA	DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI)	0.55	0.58
5	b1264	trpE	anthranilate synthase component I (NCBI)	no	0.43
6	b2019	hisG	ATP phosphoribosyltransferase (NCBI)	0.56	0.43
7	b3368	cysG	fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI)	0.34	0.42
8	b2762	cysH	phosphoadenosine phosphosulfate reductase (NCBI)	0.24	0.42
9	b2020	hisD	histidinol dehydrogenase (NCBI)	0.49	0.42
10	b2021	hisC	histidinol-phosphate aminotransferase (NCBI)	0.49	0.42
11	b2414	cysK	cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)	0.56	0.42
12	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	0.49	0.41
13	b3939	metB	cystathionine gamma-synthase (NCBI)	0.78	0.41
14	b2750	cysC	adenylylsulfate kinase (NCBI)	0.26	0.41
15	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.51	0.41
16	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.52	0.41
17	b0074	leuA	2-isopropylmalate synthase (NCBI)	0.50	0.41
18	b3008	metC	cystathionine beta-lyase (NCBI)	0.63	0.41
19	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.72	0.41
20	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.50	0.41

Or look for negative cofitness