Top cofit genes for b4244 from Escherichia coli BW25113

pyrI: aspartate carbamoyltransferase regulatory subunit (NCBI)
SEED: Aspartate carbamoyltransferase regulatory chain (PyrI)
KEGG: aspartate carbamoyltransferase regulatory subunit

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3829	metE	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI)	0.64	0.38
2	b3828	metR	DNA-binding transcriptional activator, homocysteine-binding (NCBI)	0.70	0.35
3	b3990	thiH	thiamine biosynthesis protein ThiH (NCBI)	0.42	0.32
4	b0423	thiI	thiamine biosynthesis protein ThiI (NCBI)	no	0.31
5	b2320	pdxB	erythronate-4-phosphate dehydrogenase (NCBI)	0.71	0.31
6	b0750	nadA	quinolinate synthetase (NCBI)	0.51	0.31
7	b0052	pdxA	4-hydroxythreonine-4-phosphate dehydrogenase (NCBI)	0.67	0.30
8	b3992	thiF	thiamin biosynthesis, thiazole moiety (VIMSS)	no	0.30
9	b3991	thiG	thiamin biosynthesis, thiazole moiety (VIMSS)	0.52	0.30
10	b3994	thiC	thiamine biosynthesis protein ThiC (NCBI)	0.43	0.30
11	b2574	nadB	L-aspartate oxidase (NCBI)	0.60	0.30
12	b3483	yhhH	orf, hypothetical protein (VIMSS)	no	0.28
13	b3650	spoT	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI)	0.53	0.27
14	b3993	thiE	thiamine-phosphate pyrophosphorylase (NCBI)	0.43	0.27
15	b3459	yhhK	hypothetical protein (NCBI)	0.57	0.27
16	b2564	pdxJ	pyridoxal phosphate biosynthetic protein (NCBI)	0.48	0.26
17	b4246	pyrL	pyrBI operon leader peptide (NCBI)	no	0.25
18	b0109	nadC	nicotinate-nucleotide pyrophosphorylase (NCBI)	0.49	0.25
19	b2103	thiD	phosphomethylpyrimidine kinase (NCBI)	0.45	0.25
20	b4407	thiS	sulfur carrier protein ThiS (NCBI)	0.60	0.24

Or look for negative cofitness