Top cofit genes for b4222 from Escherichia coli BW25113

ytfP: hypothetical protein (NCBI)
SEED: UPF0131 protein YtfP

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3779	gpp	guanosine pentaphosphatase/exopolyphosphatase (NCBI)	0.94	0.45
2	b3650	spoT	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI)	0.88	0.43
3	b3810	yigA	hypothetical protein (NCBI)	0.65	0.42
4	b0429	cyoD	cytochrome o ubiquinol oxidase subunit IV (NCBI)	0.35	0.34
5	b0104	guaC	guanosine 5'-monophosphate oxidoreductase (NCBI)	no	0.34
6	b0428	cyoE	protoheme IX farnesyltransferase (NCBI)	0.82	0.34
7	b1712	ihfA	integration host factor subunit alpha (NCBI)	0.64	0.33
8	b0427	yajR	putative transport protein (VIMSS)	0.46	0.33
9	b0430	cyoC	cytochrome o ubiquinol oxidase subunit III (NCBI)	0.53	0.33
10	b0081	mraZ	hypothetical protein (NCBI)	no	0.32
11	b4018	iclR	repressor of aceBA operon (VIMSS)	0.57	0.32
12	b1658	purR	DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI)	0.98	0.32
13	b3386	rpe	ribulose-phosphate 3-epimerase (NCBI)	no	0.32
14	b0431	cyoB	cytochrome o ubiquinol oxidase subunit I (NCBI)	0.77	0.32
15	b0432	cyoA	cytochrome o ubiquinol oxidase subunit II (NCBI)	0.81	0.32
16	b0243	proA	gamma-glutamyl phosphate reductase (NCBI)	0.79	0.31
17	b3390	aroK	shikimate kinase I (NCBI)	0.59	0.31
18	b2283	nuoG	NADH:ubiquinone oxidoreductase, chain G (RefSeq)	0.60	0.31
19	b3414	gntY	predicted gluconate transport associated protein (NCBI)	0.86	0.31
20	b0242	proB	gamma-glutamyl kinase (NCBI)	0.75	0.31

Or look for negative cofitness