Top cofit genes for b4177 from Escherichia coli BW25113

purA: adenylosuccinate synthetase (NCBI)
SEED: Adenylosuccinate synthetase (EC 6.3.4.4)
KEGG: adenylosuccinate synthase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3386	rpe	ribulose-phosphate 3-epimerase (NCBI)	no	0.71
2	b0118	acnB	aconitate hydratase (NCBI)	no	0.63
3	b3725	pstB	phosphate transporter subunit (NCBI)	no	0.60
4	b2822	recC	exonuclease V (RecBCD complex), gamma chain (NCBI)	no	0.57
5	b0890	ftsK	DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI)	no	0.56
6	b2820	recB	exonuclease V (RecBCD complex), beta subunit (NCBI)	no	0.55
7	b3290	trkA	potassium transporter peripheral membrane component (NCBI)	no	0.54
8	b3728	pstS	phosphate transporter subunit (NCBI)	no	0.54
9	b0200	gmhB	hypothetical protein (NCBI)	no	0.53
10	b3811	xerC	site-specific tyrosine recombinase XerC (NCBI)	0.98	0.53
11	b2894	xerD	site-specific tyrosine recombinase XerD (NCBI)	no	0.52
12	b0114	aceE	pyruvate dehydrogenase subunit E1 (NCBI)	no	0.52
13	b0439	lon	DNA-binding ATP-dependent protease La (NCBI)	0.55	0.50
14	b2564	pdxJ	pyridoxal phosphate biosynthetic protein (NCBI)	0.66	0.50
15	b1712	ihfA	integration host factor subunit alpha (NCBI)	no	0.50
16	b3204	ptsN	sugar-specific enzyme IIA component of PTS (NCBI)	0.31	0.49
17	b3828	metR	DNA-binding transcriptional activator, homocysteine-binding (NCBI)	no	0.49
18	b1693	aroD	3-dehydroquinate dehydratase (NCBI)	no	0.48
19	b4488	ilvG	no description	no	0.48
20	b0750	nadA	quinolinate synthetase (NCBI)	0.80	0.48

Or look for negative cofitness