Top cofit genes for b4005 from Escherichia coli BW25113

purD: phosphoribosylamine--glycine ligase (NCBI)
SEED: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
KEGG: phosphoribosylamine--glycine ligase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b2557	purL	phosphoribosylformylglycinamidine synthase (NCBI)	0.99	0.99
2	b2312	purF	amidophosphoribosyltransferase (NCBI)	1.00	0.98
3	b4006	purH	bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI)	0.98	0.98
4	b2499	purM	phosphoribosylaminoimidazole synthetase (NCBI)	0.99	0.97
5	b0522	purK	phosphoribosylaminoimidazole carboxylase (NCBI)	0.98	0.96
6	b0523	purE	phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI)	0.97	0.95
7	b2476	purC	phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)	0.99	0.94
8	b1062	pyrC	dihydroorotase (NCBI)	0.97	0.91
9	b0945	pyrD	dihydroorotate dehydrogenase (NCBI)	0.97	0.91
10	b1281	pyrF	orotidine 5'-phosphate decarboxylase (NCBI)	0.96	0.90
11	b3642	pyrE	orotate phosphoribosyltransferase (NCBI)	0.96	0.90
12	b4245	pyrB	aspartate carbamoyltransferase catalytic subunit (NCBI)	0.97	0.86
13	b4388	serB	3-phosphoserine phosphatase (NCBI)	0.93	0.86
14	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.96	0.85
15	b0032	carA	carbamoyl-phosphate synthase small subunit (NCBI)	0.96	0.85
16	b0907	serC	phosphoserine aminotransferase (NCBI)	0.96	0.84
17	b2329	aroC	chorismate synthase (NCBI)	0.93	0.84
18	b2913	serA	D-3-phosphoglycerate dehydrogenase (NCBI)	0.95	0.84
19	b0004	thrC	threonine synthase (NCBI)	0.96	0.83
20	b0003	thrB	homoserine kinase (NCBI)	0.94	0.83

Or look for negative cofitness