Top cofit genes for b3941 from Escherichia coli BW25113

metF: 5,10-methylenetetrahydrofolate reductase (NCBI)
SEED: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
KEGG: methylenetetrahydrofolate reductase (NADPH)

Rank Hit Name Description Conserved? Cofitness  
1 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 1.00 0.98
2 b3774 ilvC ketol-acid reductoisomerase (NCBI) 0.99 0.98
3 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.95 0.97
4 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.99 0.97
5 b2020 hisD histidinol dehydrogenase (NCBI) 0.99 0.97
6 b2600 tyrA fused chorismate mutase T/prephenate dehydrogenase (NCBI) 0.98 0.97
7 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.99 0.96
8 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.99 0.96
9 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.99 0.96
10 b2025 hisF imidazole glycerol phosphate synthase subunit HisF (NCBI) 0.99 0.96
11 b2019 hisG ATP phosphoribosyltransferase (NCBI) 0.99 0.96
12 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.98 0.95
13 b2021 hisC histidinol-phosphate aminotransferase (NCBI) 0.97 0.95
14 b0242 proB gamma-glutamyl kinase (NCBI) 0.99 0.95
15 b3960 argH argininosuccinate lyase (NCBI) 0.99 0.95
16 b2762 cysH phosphoadenosine phosphosulfate reductase (NCBI) 0.97 0.95
17 b3281 aroE dehydroshikimate reductase, NAD(P)-binding (NCBI) 0.97 0.95
18 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.99 0.95
19 b3172 argG argininosuccinate synthase (NCBI) 0.99 0.95
20 b2750 cysC adenylylsulfate kinase (NCBI) 0.90 0.95

Or look for negative cofitness