Top cofit genes for b3912 from Escherichia coli BW25113

cpxR: DNA-binding response regulator in two-component regulatory system with CpxA (NCBI)
SEED: Copper-sensing two-component system response regulator CpxR
KEGG: two-component system, OmpR family, response regulator CpxR

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b4140	b4140	orf, hypothetical protein (VIMSS)	0.39	0.61
2	b3932	hslV	ATP-dependent protease peptidase subunit (NCBI)	no	0.59
3	b2952	yggT	predicted inner membrane protein (NCBI)	0.65	0.56
4	b3038	ygiC	predicted enzyme (NCBI)	0.72	0.56
5	b3931	hslU	ATP-dependent protease ATP-binding subunit (NCBI)	0.75	0.55
6	b3611	yibN	predicted rhodanese-related sulfurtransferase (NCBI)	0.74	0.53
7	b4175	hflC	modulator for HflB protease specific for phage lambda cII repressor (NCBI)	0.88	0.51
8	b4174	hflK	modulator for HflB protease specific for phage lambda cII repressor (NCBI)	0.78	0.50
9	b3037	ygiB	conserved outer membrane protein (RefSeq)	no	0.49
10	b0970	yccA	inner membrane protein (NCBI)	no	0.48
11	b3466	yhhL	conserved inner membrane protein (NCBI)	0.54	0.47
12	b3424	glpG	predicted intramembrane serine protease (NCBI)	0.28	0.46
13	b0441	ppiD	peptidyl-prolyl cis-trans isomerase (rotamase D) (NCBI)	0.73	0.46
14	b1255	yciC	hypothetical protein (NCBI)	0.68	0.43
15	b3094	exuR	negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS)	0.32	0.43
16	b2039	rfbA	glucose-1-phosphate thymidylyltransferase (NCBI)	no	0.41
17	b2844	yqeF	putative acyltransferase (VIMSS)	no	0.39
18	b3403	pck	phosphoenolpyruvate carboxykinase (NCBI)	0.28	0.39
19	b2037	rfbX	predicted polisoprenol-linked O-antigen transporter (NCBI)	no	0.38
20	b0407	yajC	preprotein translocase subunit YajC (NCBI)	0.57	0.36

Or look for negative cofitness