Top cofit genes for b3650 from Escherichia coli BW25113

spoT: bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI)
SEED: GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
KEGG: guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3828	metR	DNA-binding transcriptional activator, homocysteine-binding (NCBI)	0.57	0.77
2	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.60	0.75
3	b2599	pheA	fused chorismate mutase P/prephenate dehydratase (NCBI)	0.58	0.75
4	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.87	0.74
5	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.94	0.73
6	b2020	hisD	histidinol dehydrogenase (NCBI)	0.93	0.73
7	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.93	0.73
8	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.59	0.73
9	b2838	lysA	diaminopimelate decarboxylase, PLP-binding (NCBI)	0.93	0.72
10	b1693	aroD	3-dehydroquinate dehydratase (NCBI)	0.86	0.72
11	b0073	leuB	3-isopropylmalate dehydrogenase (VIMSS)	0.94	0.72
12	b2019	hisG	ATP phosphoribosyltransferase (NCBI)	0.58	0.72
13	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.93	0.72
14	b3829	metE	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI)	no	0.72
15	b0075	leuL	leu operon leader peptide (NCBI)	no	0.72
16	b2600	tyrA	fused chorismate mutase T/prephenate dehydrogenase (NCBI)	0.43	0.71
17	b0074	leuA	2-isopropylmalate synthase (NCBI)	0.94	0.71
18	b2762	cysH	phosphoadenosine phosphosulfate reductase (NCBI)	0.82	0.71
19	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.93	0.71
20	b0242	proB	gamma-glutamyl kinase (NCBI)	0.88	0.71

Or look for negative cofitness