Top cofit genes for b3528 from Escherichia coli BW25113

dctA: C4 dicarboxylate/orotate:H+ symporter (DctA) (from data)
Original annotation: C4-dicarboxylate transport protein (NCBI)
SEED: Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate
KEGG: aerobic C4-dicarboxylate transport protein

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b4124	dcuR	DNA-binding response regulator in two-component regulatory system with DcuS (NCBI)	0.99	0.87
2	b4125	dcuS	sensory histidine kinase in two-component regulatory system with DcuR, regulator of anaerobic fumarate respiration (NCBI)	0.87	0.84
3	b1479	sfcA	NAD-linked malate dehydrogenase (malic enzyme) (VIMSS)	0.66	0.52
4	b3403	pck	phosphoenolpyruvate carboxykinase (NCBI)	0.81	0.41
5	b3232	yhcM	conserved protein with nucleoside triphosphate hydrolase domain (NCBI)	0.82	0.38
6	b2587	kgtP	alpha-ketoglutarate transporter (NCBI)	0.58	0.38
7	b4232	fbp	fructose-1,6-bisphosphatase (NCBI)	0.62	0.34
8	b2151	galS	DNA-binding transcriptional repressor (NCBI)	no	0.32
9	b0390	aroM	hypothetical protein (NCBI)	0.24	0.30
10	b0723	sdhA	succinate dehydrogenase flavoprotein subunit (NCBI)	0.70	0.29
11	b0721	sdhC	succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI)	0.42	0.29
12	b2283	nuoG	NADH:ubiquinone oxidoreductase, chain G (RefSeq)	0.77	0.29
13	b2278	nuoL	NADH dehydrogenase subunit L (NCBI)	0.74	0.29
14	b2284	nuoF	NADH:ubiquinone oxidoreductase, chain F (NCBI)	0.78	0.29
15	b2286	nuoC	NADH:ubiquinone oxidoreductase, chain C,D (RefSeq)	0.76	0.29
16	b3779	gpp	guanosine pentaphosphatase/exopolyphosphatase (NCBI)	no	0.28
17	b2276	nuoN	NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq)	0.72	0.28
18	b2281	nuoI	NADH dehydrogenase subunit I (NCBI)	0.75	0.28
19	b3412	bioH	carboxylesterase of pimeloyl-CoA synthesis (NCBI)	0.59	0.27
20	b2897	ygfY	hypothetical protein (NCBI)	0.63	0.26

Or look for negative cofitness