Top cofit genes for b3478 from Escherichia coli BW25113

nikC: nickel transporter subunit (NCBI)
SEED: Nickel transport system permease protein NikC (TC 3.A.1.5.3)
KEGG: peptide/nickel transport system permease protein

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3477	nikB	nickel transporter subunit (NCBI)	0.53	0.72
2	b3476	nikA	nickel transporter subunit (NCBI)	0.48	0.71
3	b3480	nikE	nickel transporter subunit (NCBI)	0.41	0.70
4	b3479	nikD	nickel transporter subunit (NCBI)	0.46	0.63
5	b2729	hypD	protein required for maturation of hydrogenases (NCBI)	0.49	0.63
6	b2712	hypF	carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases (NCBI)	0.47	0.61
7	b2994	hybC	hydrogenase 2, large subunit (NCBI)	no	0.60
8	b2995	hybB	predicted hydrogenase 2 cytochrome b type component (NCBI)	0.43	0.58
9	b2997	hybO	hydrogenase 2, small subunit (NCBI)	0.52	0.57
10	b2730	hypE	carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein (RefSeq)	0.58	0.55
11	b0239	frsA	fermentation/respiration switch protein (NCBI)	no	0.53
12	b2996	hybA	hydrogenase 2 4Fe-4S ferredoxin-type component (NCBI)	0.51	0.51
13	b0781	moaA	molybdenum cofactor biosynthesis protein A (NCBI)	no	0.49
14	b0009	mog	molybdenum cofactor biosynthesis protein (NCBI)	0.22	0.46
15	b0765	modC	molybdate transporter subunit (NCBI)	no	0.44
16	b3857	mobA	molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI)	no	0.44
17	b2727	hypB	GTP hydrolase involved in nickel liganding into hydrogenases (NCBI)	no	0.43
18	b0826	moeB	molybdopterin biosynthesis protein MoeB (NCBI)	no	0.43
19	b2993	hybD	predicted maturation element for hydrogenase 2 (NCBI)	no	0.42
20	b0785	moaE	molybdopterin synthase, large subunit (NCBI)	0.55	0.41

Or look for negative cofitness