Top cofit genes for b3389 from Escherichia coli BW25113

aroB: 3-dehydroquinate synthase (NCBI)
SEED: 3-dehydroquinate synthase (EC 4.2.3.4)
KEGG: 3-dehydroquinate synthase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3281	aroE	dehydroshikimate reductase, NAD(P)-binding (NCBI)	0.98	0.99
2	b1693	aroD	3-dehydroquinate dehydratase (NCBI)	0.97	0.97
3	b3771	ilvD	dihydroxy-acid dehydratase (NCBI)	0.92	0.94
4	b0908	aroA	3-phosphoshikimate 1-carboxyvinyltransferase (NCBI)	0.95	0.94
5	b3774	ilvC	ketol-acid reductoisomerase (NCBI)	0.92	0.94
6	b3941	metF	5,10-methylenetetrahydrofolate reductase (NCBI)	0.91	0.94
7	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.80	0.94
8	b2600	tyrA	fused chorismate mutase T/prephenate dehydrogenase (NCBI)	0.88	0.93
9	b2329	aroC	chorismate synthase (NCBI)	0.95	0.93
10	b2025	hisF	imidazole glycerol phosphate synthase subunit HisF (NCBI)	0.91	0.93
11	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.93	0.93
12	b2021	hisC	histidinol-phosphate aminotransferase (NCBI)	0.91	0.93
13	b2020	hisD	histidinol dehydrogenase (NCBI)	0.91	0.93
14	b1260	trpA	tryptophan synthase subunit alpha (NCBI)	0.91	0.93
15	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.91	0.92
16	b0073	leuB	3-isopropylmalate dehydrogenase (VIMSS)	0.90	0.92
17	b1261	trpB	tryptophan synthase subunit beta (NCBI)	0.93	0.92
18	b3960	argH	argininosuccinate lyase (NCBI)	0.85	0.92
19	b0074	leuA	2-isopropylmalate synthase (NCBI)	0.89	0.92
20	b0071	leuD	isopropylmalate isomerase small subunit (NCBI)	0.90	0.92

Or look for negative cofitness