Top cofit genes for b3146 from Escherichia coli BW25113

yraL: predicted methyltransferase (NCBI)
SEED: rRNA small subunit methyltransferase I

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b0082	mraW	S-adenosyl-methyltransferase (NCBI)	0.75	0.58
2	b4235	pmbA	predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI)	0.86	0.38
3	b0441	ppiD	peptidyl-prolyl cis-trans isomerase (rotamase D) (NCBI)	0.79	0.36
4	b3198	kdsC	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI)	0.71	0.35
5	b3933	ftsN	essential cell division protein (NCBI)	no	0.34
6	b3466	yhhL	conserved inner membrane protein (NCBI)	no	0.34
7	b2620	smpB	SsrA-binding protein (NCBI)	0.54	0.34
8	b0240	crl	DNA-binding transcriptional regulator (NCBI)	0.53	0.33
9	b2741	rpoS	RNA polymerase sigma factor (NCBI)	0.67	0.33
10	b2576	srmB	ATP-dependent RNA helicase (NCBI)	0.78	0.33
11	b3162	deaD	inducible ATP-independent RNA helicase (VIMSS)	0.54	0.33
12	b3261	fis	DNA-binding protein Fis (NCBI)	0.78	0.32
13	b0661	miaB	isopentenyl-adenosine A37 tRNA methylthiolase (NCBI)	0.75	0.32
14	b0406	tgt	queuine tRNA-ribosyltransferase (NCBI)	0.83	0.32
15	b2948	yqgE	orf, hypothetical protein (VIMSS)	0.77	0.32
16	b2101	yegW	predicted DNA-binding transcriptional regulator (NCBI)	0.26	0.31
17	b0949	uup	fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI)	0.60	0.31
18	b3872	yihL	predicted DNA-binding transcriptional regulator (NCBI)	no	0.31
19	b3244	tldD	predicted peptidase (NCBI)	0.88	0.30
20	b0382	yaiB	hypothetical protein (NCBI)	0.47	0.30

Or look for negative cofitness