Top cofit genes for b2491 from Escherichia coli BW25113

hyfR: putative 2-component regulator, interaction with sigma 54 (VIMSS)
KEGG: hydrogenase-4 transcriptional activator

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b4314	fimA	major type 1 subunit fimbrin (pilin) (NCBI)	no	0.25
2	b3898	frvX	predicted endo-1,4-beta-glucanase (NCBI)	no	0.20
3	b0934	ycbM	putative transport system permease protein (VIMSS)	no	0.19
4	b3402	yhgE	predicted inner membrane protein (NCBI)	no	0.19
5	b2224	atoB	acetyl-CoA acetyltransferase (NCBI)	no	0.18
6	b4317	fimD	outer membrane usher protein, type 1 fimbrial synthesis (NCBI)	no	0.18
7	b0756	galM	galactose-1-epimerase (mutarotase) (NCBI)	no	0.18
8	b2983	yghQ	predicted inner membrane protein (NCBI)	no	0.18
9	b4319	fimG	minor component of type 1 fimbriae (NCBI)	no	0.17
10	b1749	xthA	exonuclease III (NCBI)	no	0.17
11	b4698	mgrR	sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq)	no	0.16
12	b3534	yhjQ	cell division protein (chromosome partitioning ATPase) (pseudogene) (RefSeq)	no	0.16
13	b4347	yjiW	conserved protein (RefSeq)	no	0.16
14	b2560	yfhB	orf, hypothetical protein (VIMSS)	no	0.16
15	b0845	ybjJ	predicted transporter (NCBI)	no	0.16
16	b2674	nrdI	hypothetical protein (NCBI)	no	0.16
17	b0766	ybhA	predicted hydrolase (NCBI)	no	0.15
18	b2137	yohF	predicted oxidoreductase with NAD(P)-binding Rossmann-fold domain (NCBI)	no	0.15
19	b3679	yidK	predicted transporter (NCBI)	no	0.15
20	b0383	phoA	alkaline phosphatase (VIMSS)	0.47	0.15

Or look for negative cofitness