Top cofit genes for b2476 from Escherichia coli BW25113

purC: phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)
SEED: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
KEGG: phosphoribosylaminoimidazole-succinocarboxamide synthase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b2557	purL	phosphoribosylformylglycinamidine synthase (NCBI)	0.99	0.94
2	b2499	purM	phosphoribosylaminoimidazole synthetase (NCBI)	0.99	0.94
3	b4005	purD	phosphoribosylamine--glycine ligase (NCBI)	0.99	0.94
4	b4006	purH	bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI)	0.98	0.94
5	b2312	purF	amidophosphoribosyltransferase (NCBI)	0.99	0.93
6	b0523	purE	phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI)	0.97	0.92
7	b0522	purK	phosphoribosylaminoimidazole carboxylase (NCBI)	0.95	0.92
8	b1062	pyrC	dihydroorotase (NCBI)	0.96	0.89
9	b0945	pyrD	dihydroorotate dehydrogenase (NCBI)	0.96	0.88
10	b3642	pyrE	orotate phosphoribosyltransferase (NCBI)	0.95	0.87
11	b1281	pyrF	orotidine 5'-phosphate decarboxylase (NCBI)	0.95	0.87
12	b4245	pyrB	aspartate carbamoyltransferase catalytic subunit (NCBI)	0.95	0.84
13	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.96	0.83
14	b0032	carA	carbamoyl-phosphate synthase small subunit (NCBI)	0.93	0.83
15	b4388	serB	3-phosphoserine phosphatase (NCBI)	0.89	0.82
16	b2329	aroC	chorismate synthase (NCBI)	0.93	0.81
17	b0907	serC	phosphoserine aminotransferase (NCBI)	0.79	0.80
18	b2913	serA	D-3-phosphoglycerate dehydrogenase (NCBI)	0.89	0.80
19	b3389	aroB	3-dehydroquinate synthase (NCBI)	0.87	0.80
20	b0908	aroA	3-phosphoshikimate 1-carboxyvinyltransferase (NCBI)	0.93	0.80

Or look for negative cofitness