Top cofit genes for b2318 from Escherichia coli BW25113

truA: tRNA pseudouridine synthase A (NCBI)
SEED: tRNA pseudouridine synthase A (EC 4.2.1.70)
KEGG: tRNA pseudouridine synthase A

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b3642	pyrE	orotate phosphoribosyltransferase (NCBI)	0.60	0.50
2	b3741	gidA	glucose-inhibited division protein A (NCBI)	0.88	0.50
3	b4245	pyrB	aspartate carbamoyltransferase catalytic subunit (NCBI)	0.50	0.49
4	b1281	pyrF	orotidine 5'-phosphate decarboxylase (NCBI)	0.74	0.49
5	b0945	pyrD	dihydroorotate dehydrogenase (NCBI)	0.74	0.47
6	b1062	pyrC	dihydroorotase (NCBI)	0.77	0.47
7	b0032	carA	carbamoyl-phosphate synthase small subunit (NCBI)	0.75	0.46
8	b4171	miaA	tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI)	0.57	0.46
9	b3706	trmE	tRNA modification GTPase (NCBI)	0.84	0.45
10	b4006	purH	bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI)	0.75	0.45
11	b0033	carB	carbamoyl-phosphate synthase large subunit (NCBI)	0.76	0.45
12	b2501	ppk	polyphosphate kinase (NCBI)	0.50	0.44
13	b4005	purD	phosphoribosylamine--glycine ligase (NCBI)	0.72	0.44
14	b2557	purL	phosphoribosylformylglycinamidine synthase (NCBI)	0.73	0.44
15	b2312	purF	amidophosphoribosyltransferase (NCBI)	0.72	0.43
16	b0439	lon	DNA-binding ATP-dependent protease La (NCBI)	0.74	0.43
17	b0720	gltA	citrate synthase (NCBI)	0.81	0.43
18	b2499	purM	phosphoribosylaminoimidazole synthetase (NCBI)	0.73	0.43
19	b2476	purC	phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)	0.73	0.42
20	b0522	purK	phosphoribosylaminoimidazole carboxylase (NCBI)	0.72	0.42

Or look for negative cofitness