Top cofit genes for b2290 from Escherichia coli BW25113

yfbQ: aspartate aminotransferase (NCBI)
SEED: Alanine transaminase (EC 2.6.1.2)
KEGG: alanine-synthesizing transaminase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b1232	purU	formyltetrahydrofolate deformylase (NCBI)	0.83	0.74
2	b3773	ilvY	DNA-binding transcriptional dual regulator (NCBI)	0.89	0.68
3	b1285	gmr	modulator of Rnase II stability (NCBI)	no	0.68
4	b4013	metA	homoserine O-succinyltransferase (NCBI)	0.92	0.68
5	b3939	metB	cystathionine gamma-synthase (NCBI)	0.91	0.64
6	b2479	gcvR	transcriptional regulation of gcv operon (VIMSS)	0.59	0.63
7	b2603	yfiR	hypothetical protein (NCBI)	0.44	0.62
8	b3772	ilvA	threonine dehydratase (NCBI)	0.89	0.61
9	b3368	cysG	fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI)	0.91	0.60
10	b0113	pdhR	transcriptional regulator of pyruvate dehydrogenase complex (NCBI)	0.53	0.59
11	b2763	cysI	sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI)	0.90	0.58
12	b2026	hisI	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI)	0.82	0.58
13	b2764	cysJ	sulfite reductase, alpha subunit, flavoprotein (NCBI)	0.84	0.58
14	b3956	ppc	phosphoenolpyruvate carboxylase (NCBI)	0.94	0.58
15	b3008	metC	cystathionine beta-lyase (NCBI)	0.89	0.57
16	b0002	thrA	bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI)	0.86	0.57
17	b2751	cysN	sulfate adenylyltransferase subunit 1 (NCBI)	0.85	0.57
18	b2414	cysK	cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)	0.68	0.56
19	b3770	ilvE	branched-chain amino acid aminotransferase (NCBI)	0.99	0.56
20	b0072	leuC	isopropylmalate isomerase large subunit (NCBI)	0.99	0.56

Or look for negative cofitness