Top cofit genes for b2289 from Escherichia coli BW25113

lrhA: DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI)
SEED: LysR family transcriptional regulator lrhA

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b4480	hdfR	transcriptional regulator HdfR (NCBI)	0.40	0.59
2	b3764	yifE	hypothetical protein (NCBI)	0.81	0.56
3	b3666	uhpT	sugar phosphate antiporter (NCBI)	0.47	0.38
4	b3765	yifB	predicted bifunctional enzyme and transcriptional regulator (RefSeq)	0.64	0.37
5	b1895	yecG	universal stress protein (NCBI)	0.85	0.37
6	b0145	dksA	DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI)	0.57	0.34
7	b1643	ydhI	predicted inner membrane protein (NCBI)	no	0.31
8	b3022	b3022	predicted cyanide hydratase (NCBI)	no	0.30
9	b3747	trkD	potassium transporter (NCBI)	0.46	0.29
10	b3326	gspE	general secretory pathway component, cryptic (NCBI)	0.40	0.26
11	b2024	hisA	N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS)	0.72	0.26
12	b2762	cysH	phosphoadenosine phosphosulfate reductase (NCBI)	0.68	0.26
13	b1284	yciT	predicted DNA-binding transcriptional regulator (NCBI)	no	0.26
14	b1707	ydiV	hypothetical protein (NCBI)	0.68	0.26
15	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.74	0.25
16	b0242	proB	gamma-glutamyl kinase (NCBI)	0.81	0.25
17	b0243	proA	gamma-glutamyl phosphate reductase (NCBI)	0.81	0.25
18	b2414	cysK	cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)	0.73	0.25
19	b2340	sixA	phosphohistidine phosphatase (NCBI)	no	0.25
20	b2021	hisC	histidinol-phosphate aminotransferase (NCBI)	0.72	0.25

Or look for negative cofitness