Top cofit genes for b2289 from Escherichia coli BW25113

lrhA: DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI)
SEED: LysR family transcriptional regulator lrhA

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b4480	hdfR	transcriptional regulator HdfR (NCBI)	0.43	0.58
2	b3764	yifE	hypothetical protein (NCBI)	0.81	0.56
3	b3666	uhpT	sugar phosphate antiporter (NCBI)	0.47	0.39
4	b1895	yecG	universal stress protein (NCBI)	0.85	0.37
5	b3765	yifB	predicted bifunctional enzyme and transcriptional regulator (RefSeq)	0.64	0.36
6	b0145	dksA	DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI)	0.47	0.32
7	b1643	ydhI	predicted inner membrane protein (NCBI)	no	0.31
8	b3022	b3022	predicted cyanide hydratase (NCBI)	no	0.29
9	b3747	trkD	potassium transporter (NCBI)	0.46	0.28
10	b3326	gspE	general secretory pathway component, cryptic (NCBI)	0.40	0.27
11	b1284	yciT	predicted DNA-binding transcriptional regulator (NCBI)	no	0.26
12	b2684	mprA	DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI)	no	0.26
13	b1707	ydiV	hypothetical protein (NCBI)	0.44	0.25
14	b2340	sixA	phosphohistidine phosphatase (NCBI)	no	0.25
15	b2024	hisA	N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS)	0.72	0.25
16	b2762	cysH	phosphoadenosine phosphosulfate reductase (NCBI)	0.68	0.24
17	b2022	hisB	imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS)	0.74	0.24
18	b0242	proB	gamma-glutamyl kinase (NCBI)	0.81	0.24
19	b2414	cysK	cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)	0.73	0.24
20	b3089	sstT	sodium:serine/threonine symporter (NCBI)	0.67	0.24

Or look for negative cofitness