Top cofit genes for b2260 from Escherichia coli BW25113

menE: O-succinylbenzoic acid--CoA ligase (NCBI)
SEED: O-succinylbenzoic acid--CoA ligase (EC 6.2.1.26)
KEGG: O-succinylbenzoic acid--CoA ligase

Rank	Hit	Name	Description	Conserved?	Cofitness
1	b2261	menC	O-succinylbenzoate synthase (NCBI)	0.91	0.63
2	b2264	menD	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase (NCBI)	0.92	0.63
3	b3289	rsmB	16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI)	no	0.39
4	b2952	yggT	predicted inner membrane protein (NCBI)	no	0.37
5	b4241	treR	trehalose repressor (NCBI)	no	0.35
6	b2844	yqeF	putative acyltransferase (VIMSS)	no	0.34
7	b4140	b4140	orf, hypothetical protein (VIMSS)	0.47	0.34
8	b3038	ygiC	predicted enzyme (NCBI)	no	0.34
9	b3497	yhiQ	predicted SAM-dependent methyltransferase (NCBI)	0.50	0.33
10	b3423	glpR	DNA-binding transcriptional repressor (NCBI)	0.72	0.33
11	b4308	yjhR	KpLE2 phage-like element; predicted frameshift suppressor (NCBI)	no	0.32
12	b2775	yqcE	predicted transporter (NCBI)	no	0.32
13	b4039	ubiC	chorismate lyase (VIMSS)	0.48	0.31
14	b1187	fadR	fatty acid metabolism regulator (NCBI)	0.46	0.31
15	b2262	menB	naphthoate synthase (NCBI)	0.91	0.31
16	b3037	ygiB	conserved outer membrane protein (RefSeq)	no	0.31
17	b2927	epd	D-erythrose 4-phosphate dehydrogenase (NCBI)	0.51	0.31
18	b1442	ydcU	predicted spermidine/putrescine transporter subunit (NCBI)	no	0.31
19	b2039	rfbA	glucose-1-phosphate thymidylyltransferase (NCBI)	no	0.31
20	b3673	emrD	2-module integral membrane pump; multidrug resistance (VIMSS)	0.55	0.30

Or look for negative cofitness